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Anti depressants Effexor EFFEXOR Venlafaxine, formerly sold as Effexor, is a prescription drug used to treat depression, anxiety, social phobia, and panic disorder. Discontinuation of Treatment with Effexor Discontinuation symptoms have been systematiy evaluated in patients taking Effexor. Effexor has been reported to be excreted in human milk. Because of the potential for serious adverse reactions in nursing infants from Effexor, a decision.