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Prozac vs. Zoloft - Healtine Sertraline is a medication used to treat depression, obsessive-compulsive disorder, panic disorder, and post-traumatic stress disorder. Sertraline belongs to the class of antidepressants known as selective serotonin reuptake inhibitors (SSRIs). Aug 10, 2016. Prozac and Zoloft are drugs used to treat depression and other conditions. The generic version of Prozac is fluoxetine, while the generic version of Zoloft is. Prozac is more likely to cause dry mouth and sleep problems.
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