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Soft tissue concentrations of ciprofloxacin in obese and lean. Ciprofloxacin is a type of medicine ed a quinolone antibiotic. OBJECTIVE To investate whether weht adjusted ciprofloxacin dosing results in. Tissue penetration, expressed as AUCtissue/AUCplasma ratio was.
Determination of ciprofloxacin in human gingival crevicular fluid by OBJECTIVE: To investate whether weht adjusted ciprofloxacin dosing results in comparable target site concentrations in obese and lean subjects. SUBJECTS: Twelve obese subjects (mean weht 122kg ciprofloxacin. Were in the range 96.33–102.67% for ciprofloxacin at the concentrations given above and the detection limit corresponding to a snal-to-noise ratio of 31 was 3.