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Common Side Effects of Combivent Respimat Ipratropium Bromide and. Treatment of chronic obstructive pulmonary disease (COPD) in patients on regular bronchodilator who continue to have bronchospasm and require second bronchodilator Aerosol: 100 mcg/20 mcg (1 actuation of metered-dose inhaler) q6hr; not to exceed 6 actuations/day Nebulizer solution: 3 m L inhaled q6hr; not to exceed 3 m L q4hr Upper respiratory tract infection (1-10%) Lung disease (6%) Headache (3-6%) Dyspnea (2-5%) Nasopharyngitis (4%) Cough (3-4%) Pharyngitis (2-4%) Pain (1-3%) Chest pain (2.6%) Sinusitis (2.3%) Nausea (1-2%) Diarrhea (1.8%) Urinary tract infection (1.6%) Influenza (1.4%) Leg cramps (1.4%) Nausea (1.4%) Pneumonia (1.4%) Rhinitis (1.1%) Allergic-type reactions, such as skin reactions (eg, rash, pruritus, urticaria [including giant urticaria]), angioedema (eg, of tongue, lips, face), laryngospasm, and anaphylaxis Angina Arrhythmia Arthralgia Dizziness Dry mouth Dyspepsia Dysphonia Edema Fatue Hypertension Insomnia Nervousness Palpitation Paresthesia Tachycardia Tremor Vomiting Cardiovascular: Palpitations, hypotension, myocardial infarction, decreased diastolic blood pressure (BP), increased systolic BP General: Anaphylactoid reactions, drowsiness, flushing, alopecia, edema, hypokalemia, mental disorder, hyperhidrosis, metabolic acidosis (with albuterol products), asthenia Gastrointestinal (GI): Mucosal ulcers, stomatitis, heartburn, distress (diarrhea, nausea, vomiting), GI motility disorder, constipation Muscular: Muscle spasms, muscular weakness, myalgia Neurologic and psychiatric: Central nervous system (CNS) stimulation, coordination difficulty Other: Throat irritation, dry throat, hoarseness Renal: Urinary retention Respiratory: Bronchospasm (including paradoxical bronchospasm), nasal congestion, drying of secretions, wheezing, exacerbation of COPD symptoms Sensory: Mydriasis, precipitation or worsening of narrow-angle glaucoma, glaucoma, increased intraocular pressure (IOP), acute eye pain, halo vision, blurred vision, accommodation disorder, ocular irritation, corneal edema, conjunctival hyperemia Paradoxical bronchospasm; discontinue immediately, and administer alternative therapy History of cardiovascular disorders; beta-adrenergic stimulation can result in cliniy snificant cardiovascular effects, myocardial ischemia, or electrocardiographic (ECG) changes Avoid spraying into eyes, and contact physician if visual disturbances (eg, blurred vision or halos) occur; monitor patients with narrow-angle glaucoma May produce cliniy important hypokalemia leading to adverse cardiovascular effects in some patients May cause immediate hypersensitivity reaction (urticaria, angioedema, rash, bronchospasm, anaphylaxis, or oropharyngeal edema); discontinue immediately, and administer alternative therapy Prostatic hyperplasia or bladder-neck obstruction Convulsive disorders, hyperthyroidism, or diabetes mellitus Do not exceed recommended dosage; fatalities have been reported in association with excessive use of inhaled sympathomimetic drugs in patients with asthma Keep out of reach of children Avoid freezing Albuterol: Beta2-adrenergic bronchodilator Ipratropium: Anticholinergic (parasympatholytic) agent; inhibits vagally mediated reflexes by antagonizing acetylcholine action; prevents increase in intracellular calcium concentration caused by interaction of acetylcholine with muscarinic receptors on bronchial smooth muscle Half-life: Albuterol, 3.6 hr (after 30-min infusion of 1.5 mg); ipratropium, 2 hr (after inhalation or IV administration) Mean clearance: Albuterol, 439 m L/min/1.73 m² Excretion: Albuterol, urine (27%); ipratropium, urine (4%) The above information is provided for general informational and educational purposes only. Side effects of Combivent Respimat include headache, cold symptoms stuffy nose, sneezing, cough, or sore throat, flu-like symptoms, nausea, vomiting.
Combivent Respimat albuterol/ipatropium dosing, Salbutamol and ipratropium belong to the family of medications known as bronchodilators. Brand and Other NamesCombivent Respimat. Classes. Dosage Forms & Strengths. albuterol. aerosol metered-dose inhaler Combivent Respimat.
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